1/31/2024 0 Comments The calex familyWe conclude that inphase and out-of-phase MRI can provide similar vertebral BMF estimation as H-1 MRS, indicating that this technique is a potentially useful tool in both research and clinical practice.Ībstract = "Inphase and out-of-phase magnetic resonance imaging is a robust and fast method which can provide similar vertebral bone marrow fat estimation as H-1 proton magnetic resonance spectroscopy, indicating that this technique is a potentially useful tool in both research and clinical practice.The importance of evaluating bone marrow fat lies in the fact that osteoporosis and obesity, two disorders of body composition, are growing in prevalence. Girls had a significantly lower vertebral BMF than mothers and fathers with both methods (for all, p <0.001). The mean differences between H-1 MRS and inphase and out-of-phase MRI in the axial and sagittal planes were relatively small, at 4.13 and 2.67 %, and the agreement between techniques was 89.4 and 93.2 %, respectively. Positive correlations were found between H-1 MRS and inphase and out-of-phase MRI in the axial plane (r = 0.746, p <0.001) and sagittal plane (r = 0.804, p <0.001). Signal intensity on the inphase and out-of-phase MRI was analyzed from the same location and size of the single-voxel H-1 MRS measurement. We compared vertebral bone marrow fat (BMF) content assessed by inphase and out-of-phase MRI and H-1 MRS using a 1.5-T MRI scanner in mothers (n = 34, aged 49.4 years), fathers (n = 31, aged 53.1 years) and their daughters (n = 40, aged 20.3 years) who participated in the CALEX family study. Bone fat mass can be reliably assessed using proton magnetic resonance spectroscopy (H-1 MRS), but this method is technically demanding and needs advanced post-processing unlike inphase and out-of-phase magnetic resonance imaging (MRI), which is a robust and fast method. The importance of evaluating bone marrow fat lies in the fact that osteoporosis and obesity, two disorders of body composition, are growing in prevalence. Inphase and out-of-phase magnetic resonance imaging is a robust and fast method which can provide similar vertebral bone marrow fat estimation as H-1 proton magnetic resonance spectroscopy, indicating that this technique is a potentially useful tool in both research and clinical practice.
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